Best Prescription Diet Pills – Comparisons and Choices

This article is intended to provide information about prescription-only diet pills and current legal and safety issues. We provide links to relevant resources as the situation may change. We strongly recommend that you visit the manufacturer’s website or the link provided for current and updated information.

There are several brands of prescription diet pills. All of this is for your doctor’s use only.

Today, people who are dieting only have to search online and they are inundated with a dizzying array of options for diet pills.

However, those who seek help from their doctor or GP are likely to get advice on diet and exercise, but unless they are already seriously overweight or their obesity is exacerbating another health problem, they are unlikely to get a prescription for diet pills.

Few of these pills are approved worldwide (United States, United Kingdom, Canada and Australia), and some that were previously approved have since been found to be unsafe, so even if the situation requires a prescription, options will likely be limited to a few approved diet pills.

There are over-the-counter diet pills that have the same mechanism of action as those commonly used in medicine.

Prescription diet pills are drugs that can be great for weight loss, but can also cause other problems in the form of side effects. Therefore, a valid prescription is required after consulting a doctor.

Xenical is the brand name version of the weight loss drug Orlistat. It is only available through a GP and is usually only prescribed to patients who are so obese that their body mass index (BMI) is 30% or more. It helps you lose weight by blocking dietary fats and is very effective in this regard.

Xenical is (along with phentermine) one of the most prescribed diet pills in the world. Cannot be purchased without a prescription. You can find ads on the Internet claiming to supply or sell Xenical, Orlistat – be very careful, it will most likely be an authentic product you will buy.

How xenophobia works

Xenical is meant to be used as part of a comprehensive weight management program that includes a healthy diet and regular exercise. The prescribing physician will likely make recommendations about diet and level of physical activity. Xenical comes in tablet form and is usually taken three times a day, immediately before fatty meals.

Fat contains a lot of calories. For every gram of fat you eat, there are nine. A diet that contains too much fat can quickly give your body more calories than it needs. Excess calories are then stored as body fat. Xenical can disrupt this process by limiting the amount of calories from fatty foods.

After ingestion, Xenical enters the intestines where it acts on the enzymes (lipases) that are needed for the breakdown of dietary fats and changes their function. Three doses (120 mg) per day can block up to 30% of dietary fat. Instead of excreting the calories, the blocked fat simply passes through the intestines and is excreted in the stool.

In a 12-month study, subjects were placed on a strict low-calorie diet and given three doses of Xenical per day. Members of the placebo group had to follow the same dietary restrictions. At the end of the study, the placebo group managed to lose weight, but with Xenical they lost twice as much weight.

Xenical fitness

While Xenical can provide a solid block of fat, it may not be the best option for people who already follow a healthy, low-fat lifestyle with low-calorie foods, as there isn’t much to go on.

Xenical is also not suitable for pregnant or breastfeeding women and may be problematic for people with certain conditions, such as liver or kidney disease and diabetes.

The prescribing doctor will likely be aware of any conditions that may make Xenical an unsuitable option, but not all patients keep their doctor informed of any changes in their condition. It is important that your doctor is informed of any changes so he or she can be sure that Xenical is the best option.

Side effects of Xenic

Xenical can cause a number of side effects, some of which are serious, and it is important that patients inform their doctor if any adverse problems occur. In this case the doctor will be better able to decide if Xenical therapy is still the best option.

Xenological side effects may include :

  • Respiratory difficulties
  • Kidney problems
  • Swollen lips, face or throat
  • swollen ankles
  • pain in urine
  • blood in urine
  • I’m tired.
  • Nausea
  • Abdominal pain

Everyone reacts differently to medications, and some Xenical users may have few or no negative problems. However, due to the action of the pill, most users will notice a difference in the texture of the stool, which will likely be softer and greasier than normal.

Changes in bowel movements are a good indicator of how well the ingredients are working, but problems can arise if consumers do not make healthy changes in their diets. If there is a large amount of fat, the amount of fat is increased until it is fixed.

This can have a very laxative effect, making the need for the toilet so great that it can overwhelm users.

The consequences of this situation can be unpleasant to say the least and, depending on where and when the need arises, cause indescribable embarrassment. That is why Xenical should never be considered a cheat pill or a magic ticket that allows the wearer to eat whatever they want while losing weight.

Other matters

By blocking fat digestion, Xenical may also prevent the absorption of beta-carotene and some fat-soluble vitamins, which are essential for good health. This problem can be easily solved with a good multivitamin, which should be taken a few hours before or after taking Xenical.

Where to buy Xenical Orlistat

As mentioned above, it is not available in stores or online.

Reduction and compliance

The diet pills Reductil (sibutramine) and Acomplia were extensively tested before they became available as prescription weight loss drugs, but both had to be withdrawn from the market when they were linked to dangerous side effects that studies could not detect.

Reductil is an appetite suppressant that works by increasing serotonin levels. Its use was first permitted in 2001, but it was later found to increase the risk of heart attacks and strokes.

About 3,000 adverse events have been reported since administration.

Acomplia is also an appetite suppressant, but it also promotes weight loss by blocking receptors in the endocannabinoid system, which affects the processes needed to regulate energy balance and the metabolism of sugars and fats.

Acomplia has since been withdrawn from the market at the request of the marketing authorisation holder. Its use has been found to lead to mental health problems and suicidal tendencies.

Acomplia is a trade name of Rimonabant, also known as SR141716.


Orlistat is generally sold under the brand name Xenical (see above). It can interfere with the normal functioning of digestive enzymes that process fats from food. Each gram of fat provides nine calories, so by interfering with digestion, Orlistat can be very effective in reducing the amount of calories your body takes in.

The fact that doctors prescribe it is the best indication of its effectiveness, but it is not a magic pill. The prescribing doctor usually also prescribes a strict diet and exercise program.

Although Orlistat is considered a safe prescription pill for weight management, the limitations of its availability are not unfounded. This can lead to a number of side effects and requires expert supervision.

Possible side effects of Orlistat are as follows:

  • Swelling of the lips, face and throat….
  • Kidney problems
  • pain in urine
  • Respiratory difficulties
  • blood in urine
  • Abdominal pain
  • swollen ankles
  • Tired
  • Nausea


Phentermine has a reputation for suppressing appetite, making it one of the most sought after diet pills in the world. However, it is closely related to amphetamine and can be equally addictive, so the reasons for prescribing it need no further explanation.

Phentermine suppresses appetite by causing the release of specific hormones that are normally only released when the body’s need for self-preservation allows it to suppress hunger pangs that could otherwise be a dangerous distraction.

This ability, known as the fight-or-flight response, has been an integral part of the human genetic makeup since the earliest days of man, when dangerous situations were part of everyday life. Phentermine’s ability to bypass the danger and stimulate the release of hormones per pill makes it a valuable weight loss pill, but like Orlistat, it is meant to be used in conjunction with diet and exercise and may as well have unpleasant side effects.

Side effects of phentermine may include:

  • Changes in bowel movements (constipation/diarrhea)
  • Unpleasant taste in the mouth
  • changes of heart
  • swelling of the feet or legs
  • High blood pressure
  • Shortness of breath
  • Walking problems
  • Skin Irritation
  • libido loss
  • The beating heart
  • Headache
  • Dry mouth
  • Chills
  • Naughty
  • Insomnia
  • Nervousness
  • Vertigo

If the potential for so many of the side effects associated with pills is addictive, it can be considered a risky choice, but used properly, under a doctor’s supervision, the potential benefits outweigh the potential downsides.

Latest thoughts on phentermine

With so many supplements for weight management, it’s surprising how limited the options are when it comes to prescription drugs. It’s basically a simple battle between the two, with phentermine being the most commonly prescribed weight loss drug.

This is a fact that in no way detracts from the capabilities of Orlistat. Fat blockers are especially useful for treating people who follow a high-fat diet. Some diets get their excess calories from other sources, but phentermine’s ability to suppress appetite can be effective in diets of all kinds – even diets that love fatty foods.

When there is no appetite, less food is consumed, whether it is high in fat or sugar and starch. Therefore, phentermine is probably the more useful of the two weight management medications currently available by prescription. In recent years, alternatives to Phentermine have appeared on the market – natural weight loss pills that can be purchased over the counter.


Contrave is a prescription weight loss drug developed in the United States by Orexigen Therapeutics. In 2014, the FDA approved the drug for use in the United States, and the Committee for Medicinal Products for Human Use (CHMP) approved its use in Europe the following year.

Unlike many other prescription diet pills, such as phentermine and Belvik, which contain only one substance, Contrave is a combination of two parts – buprione and naltrexone. Buprion is primarily used as an antidepressant and can also help you deal with the stress of quitting smoking. Naltrexone is commonly used to treat alcohol and opioid addiction. Nevertheless, both pills have proven their potential as a means to lose weight, but they can also cause certain side effects, and some of these negative problems are tolerated when the two substances are combined.

Contrave is probably similar in potential to the weight loss product Qsymia, but may be more effective than Belviq. Compared to clinical trials, subjects taking Xymia reduced their body weight by an average of 9%. Volunteers recruited to the Belviq clinical trial showed an average weight loss of 3%. Somewhere in between, a contradiction occurred, and the subjects showed an average weight loss of 5%.

Permissibility of prescription slimming products

As with other diet pills, doctors must follow strict guidelines when deciding whether to write a prescription. Contraception can only be used in adult patients with a body mass index (BMI) of 30 or higher. People with a BMI of 27 to 30 may still benefit from Contrave treatment if they have at least one weight-related condition, such as diabetes or high blood pressure. If the patient has not lost at least 5% of their body weight after 12 weeks of treatment, treatment with Contrave will be discontinued due to weight loss.

How Contraveworks

Contrave is an appetite suppressant drug that targets the neural pathways that influence appetite and food consumption. Its ability to suppress appetite has been investigated in a number of early clinical trials. A total of 4,500 obese people participated in these studies. Some had to do with weight, some did not.

Treatment lasted 12 months, and all participants followed a low-calorie diet and exercised regularly. The results showed that the subjects who received Contrave lost an average of 4.1% more weight than the placebo group.

Directions for use contrava capsules – Contrava capsules should always be swallowed whole and should never be chewed. The usual dose is four capsules per day, but new users should start with a reduced dose and gradually increase it over a number of weeks.

  1. Week one: One capsule every morning.
  2. Week two: One capsule every morning and one capsule in the evening.
  3. Week three: Two capsules in the morning and one capsule in the evening.
  4. Week 4 is coming up: Two capsules in the morning and two capsules in the evening.

Confrontation should be used as part of the overall weight management process, which includes a healthy diet and regular exercise. The doctor prescribing Contrave will recommend both based on each patient’s mobility and fitness level.

It is also important not to eat foods that are high in fat, as this can lead to an attack.

Adverse reactions and fitness issues

A prescription is not for everyone and the decision to issue a prescription will not be based solely on an official recommendation. Each patient’s medical history is taken into account, as well as the medications he or she is currently taking.

Among other things, it is not suitable for pregnant women and people suffering from certain diseases:

  • Eating disorders
  • Attacks
  • High blood pressure
  • Cardiovascular diseases

Contrave is also not suitable for use with certain medications, including :

  • Other products containing bupropion
  • Opioids or preparations for treatment of opioid addiction

For people who drink a lot of alcohol, Contrave can also be problematic because drinking Contrave with a lot of alcohol can cause seizures. However, people who are used to drinking large amounts of alcohol and then suddenly cut back have an increased risk of cramps, even if they use contraceptives.

Some of the most common side effects that Contrave users may experience include

  • Nausea
  • Vertigo
  • Diarrhea
  • Vomit
  • Headache
  • Dry mouth
  • Sleep problems
  • Request

However, potential users should be aware that Contrave may have other frightening side effects, including suicidal thoughts and tendencies.


Belvik is a weight loss pill that can only be purchased legally with a doctor’s prescription. The FDA approved its use in 2012, but it didn’t become available until the following year. It is manufactured by Arena Pharmaceuticals and Belvik is the brand name, generic name of the product Lorcaserin.

Dieters using Belviq can expect to lose 3 to 3.7% of their body weight in one year. However, studies have shown that weight loss can return fairly quickly after the end of treatment. In one study, patients prescribed Belvik for one year managed to lose 5% of their weight, but by the end of the following year, the patients had regained 50% of the weight they had lost by using Belvik. So in this regard, Belvik is not comparable to some other prescription weight loss drugs, such as phentermine and orlistat.

Right to treatment

The Food and Drug Administration (FDA) approved Belvik for prescription use, but is now calling for a recall. As is usually the case with these medications, they should be used in conjunction with a healthy diet and exercise program and are only appropriate for adults.

There are other limitations as well. To be eligible for treatment with Belvik, patients must have a body mass index (BMI) of at least 30. Some patients with a BMI between 27 and 30 may also qualify, but only if they have at least one weight-related condition. Some examples: high cholesterol, high blood pressure and diabetes.

How Belvik works

Belvik works by causing changes in the action of the neurotransmitter serotonin.

Serotonin can affect mood, and many pills that can stimulate serotonin changes also appear to be able to affect appetite, allowing people to maintain a low-calorie diet without feeling hungry. Capsules or supplements that can suppress appetite can often help people reduce their daily caloric intake enough to cause a caloric deficit, burning fat in the body for extra energy. However, for best results, appetite suppressants should be used in conjunction with a healthy diet and exercise.

Directions for use of Belviq – One 10 mg tablet is required twice daily. If there is no reduction in body weight by 5% after 12 weeks of treatment, the prescriber will not write a prescription again.

Adverse reactions and fitness issues

Belvik is not for everyone, no matter how bad it gets. It is not suitable for pregnant women or women caring for a child. The Food and Drug Administration (FDA) has established a number of categories regarding the dangers certain drugs may pose to an unborn baby. Belvik is a category X drug that may pose a serious risk to the fetus.

Some users may be allergic to the active ingredient (lorcaserin) and others may not be suitable candidates due to existing medical conditions.

Here are a few examples:

  • Heart valve disease
  • Hart’s stagnant margin of error
  • Sickle cell disease
  • Kidney and liver diseases
  • Leukaemia
  • Peyron’s disease (malformation of the penis)

Like phentermine, Belviq can be addictive, so it may not be a suitable weight loss option for people with a history of drug abuse and addiction problems.

Anyone considering using Belviq to lose weight should also be aware that the products have been linked to certain side effects, some of which can affect the mind and body.

Taking Belviq can affect memory and the ability to focus the mind on a task. It can also cause hallucinations, which is why the manufacturer advises new users not to drive or operate machinery until they are sure it will not compromise their safety.

Other side effects may occur with the use of Belviq:

  • Headaches.
  • Vertigo
  • Feelings of fatigue
  • Dry mouth
  • Nausea
  • Back pain
  • Request
  • Depression
  • Suicidal thoughts
  • Hypoglycemia (low blood sugar)
  • A slow heartbeat
  • Painful erections


Xymia is a prescription weight loss medication that contains a combination of phentermine and topiramate. The first is an appetite suppressant and the second is an anticonvulsant sometimes used to treat children with epilepsy. It appears to contribute to some degree of weight loss as a side effect, but topiramate is also known to cause birth defects.

While many weight loss medications need to be taken twice or more a day, Xymia only needs to be taken once because it is designed to release both medications evenly throughout the day, rather than all at once.

A brief history of Xymia

Qsymia was developed by Vivus, a California-based pharmaceutical company. It was submitted to the FDA for approval in December 2009, but the FDA rejected it in its current form the following October, citing concerns about side effects, including increased heart rate, birth defects and cardiovascular side effects.

These side effects are still a problem, but after the new presentation of Vivus 2011. The FDA approved the use, and in September 2012. Qsymia is now available as a prescription drug. The European regulatory authorities have not been so lenient on potentially defective products and have refused to approve the use of Qsymia in Europe.

Right to treatment

The U.S. Food and Drug Administration (FDA) has approved Xymia only for the treatment of chronic obesity, and the pills must be used in conjunction with a low-calorie diet and exercise.

People with a BMI of less than 27 are not eligible for treatment with Xymia, and people with a BMI between 27 and 30 are only eligible if they also have weight-related health problems.

High blood pressure, for example. However, people with a BMI of 30 or more may be eligible for treatment with Xenia even if they do not have such health problems.

How does Xymiawork?

The exact effect is unknown, but phentermine is an appetite suppressant that works by causing changes in the brain that trigger a state called fight or flight.

It seems likely that Xymia could share that ability. It has also been suggested that the product may cause other changes that speed up metabolism and prompt the body to burn calories faster than normal. While nothing is certain, the combination of appetite suppression and rapid calorie burning may cause your body to burn its own fat.

However, despite the confusion over the mechanisms involved, Xymia seems to work for weight loss. After a 12-month clinical trial, obese patients receiving a lower dose (23 mg) of Xymia lost 8.4% of their body weight. Patients receiving the highest dose (46 mg) reduced their body weight by 10.6%.

Recommendations for use of Xymia – The starting dose is one 23 mg capsule, taken every morning. After 14 days, the strength of the capsule is increased to 46 mg. If the patient is under 12 years of age. If the patient has not lost at least 3% of their body weight during the first week of use, they will not be supplied again.

Adverse reactions and fitness issues

Xymia is not suitable for some people, even if their weight has become uncontrollable. First, it should never be used by pregnant women. It can also be addictive and is not suitable for patients with high blood pressure or heart, liver or kidney disease.

Other medical conditions that may make Xymia an unsuitable option are

  • Glaucoma
  • Depression
  • Diabetes
  • Convulsions or epilepsy
  • Low bone mineral density
  • Kidney stones
  • overactive thyroid

It may also react badly to some medications, including MAOIs, and women taking birth control pills may experience irregular vaginal bleeding.

Side effects can also be a problem for many users, and some of these effects can be quite frightening.

Some of the known side effects include:

  • Respiratory difficulties
  • Swelling of the tongue, lips and face ….
  • A beating heart
  • A trembling heart
  • Sudden eye pain and/or vision problems
  • problem clustering
  • Weak language
  • Convulsions
  • Memory problems
  • Extreme thirst
  • Vertigo
  • Anxiety
  • Hypoglycemia (low blood sugar)
  • Headache
  • Sleep problems
  • Request
  • dry mouth
  • Numbness
  • tingling feeling

frequently asked questions

Which diet pills are the most effective prescription diet pills?


What is the number one prescription diet pill?

CONTRAVE® is an FDA-approved prescription drug that can help overweight adults (with a weight-related medical condition) lose and maintain their weight. Use with diet and exercise.

Which diet pill is most similar to phentermine?

While PhenQ is getting the most rave reviews and is fast becoming the best alternative to prescription diet pills like phentermine (and ephedra), Lean Optimizer, on the other hand, is one of the products whose ingredients best target drugs and whole hormones (leptin and ghrelin).

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